Annealed DNA motif optimization
Annealed search for fixed-length DNA sequences that balance multiple transcription-factor motifs and export assay-ready candidates.
Projects
Active learning links DNA sequence to condition-dependent gene expression
Closed-loop sequence-to-expression modeling to accelerate promoter engineering with fewer experiments.
Designing information-dense promoters by packing overlapping binding sites
De novo promoter sequence design via nucleotide string packing and integer linear programming.
High-throughput co-culture screening maps cross-feeding in synthetic yeast communities
I designed a lab-automation workflow to screen thousands of pairwise co-cultures across an auxotrophic yeast knockout library.
Four-input transcriptional control of the MVA pathway for limonene production
A multi-inducer circuit for systematic pathway tuning in E. coli.
